Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548918 | 0.76 | MEN1 (0.47) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20095815 | 0.72 | TDP1 (0.63) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL8908479 | 0.69 | TDP1 (0.48) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19824265 | 0.68 | TDP1 (0.49) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5327354 | 0.68 | TDP1 (0.57) | TDP1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL22488319 | 0.68 | TDP1 (0.47) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL571043 | 0.68 | TDP1 (0.52) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20283250 | 0.68 | TDP1 (0.57) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL17934112 | 0.68 | TDP1 (0.57) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL6201668 | 0.68 | CTSK (0.40) | TDP1KMT2ACA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |