Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879203 | 1.00 | MPO (0.58) | MPOKDM4EALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5879295 | 0.99 | MPO (0.57) | MPOKDM4EALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5879263 | 0.99 | MPO (0.57) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL5879141 | 0.83 | CHEK1 (0.59) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5879183 | 0.81 | ALDH1A1 (0.56) | MPOKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL11733209 | 0.80 | MPO (0.59) | MPOKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5879324 | 0.79 | ALDH1A1 (0.56) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL5879158 | 0.78 | CHEK1 (0.71) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5879307 | 0.77 | CHEK1 (0.49) | MPOKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL5879140 | 0.77 | CHEK1 (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411057-B1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-04-27 | — | — | EP | disclosed |
| EP-1411057-A1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2004-04-21 | — | — | EP | disclosed |