Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366693 | 0.89 | GAA (0.70) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL15063248 | 0.77 | GAA (0.96) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1808956 | 0.77 | GAA (0.96) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL628011 | 0.77 | GAA (0.96) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2554530 | 0.77 | GAA (0.96) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6200634 | 0.77 | ADRB2 (0.56) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6203010 | 0.76 | CYP2C19 (0.82) | GAALMNAALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2988022 | 0.76 | GAA (1.00) | GAALMNAALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL629184 | 0.76 | GAA (1.00) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL628330 | 0.76 | LMNA (0.96) | GAALMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |