Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520271 | 0.90 | POLB (0.60) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11526582 | 0.90 | ALDH1A1 (0.55) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11527507 | 0.90 | KMT2A (0.58) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11733805 | 0.90 | POLB (0.60) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11521612 | 0.90 | POLB (0.58) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29110265 | 0.88 | KMT2A (0.60) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29110155 | 0.88 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29110239 | 0.88 | POLB (0.60) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29110188 | 0.88 | POLB (0.61) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL28367385 | 0.87 | POLB (0.62) | LMNASMN1; SMN2ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677443-B | Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation | 中国科学院理化技术研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-115677443-A | Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation | 中国科学院理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |
| WO-2021043994-A1 | SYNTHESIS METHOD USING CARBENES IN AN AQUEOUS MEDIUM AND APPLIED TO BIOMOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-03-11 | — | — | WO | disclosed |
| CN-106966877-B | 1, 4-dicarbonyl compound and preparation method thereof | 郑州大学 | 2020-02-07 | — | — | CN | disclosed |
| US-10294203-B2 | Organic compound and electronic device comprising an organic layer comprising the organic compound | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-05-21 | — | — | US | disclosed |
| US-20170334849-A1 | ORGANIC COMPOUND AND ELECTRONIC DEVICE COMPRISING AN ORGANIC LAYER COMPRISING THE ORGANIC COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334849-A1 | ORGANIC COMPOUND AND ELECTRONIC DEVICE COMPRISING AN ORGANIC LAYER COMPRISING THE ORGANIC COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |
| WO-1996022075-A1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-07-25 | — | — | WO | disclosed |
| US-4035395-A | Process for the preparation of ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334849-A1 | ORGANIC COMPOUND AND ELECTRONIC DEVICE COMPRISING AN ORGANIC LAYER COMPRISING THE ORGANIC COMPOUND | OR10J3, OCIAD2, OCIAD1 | LMNA 2565/4885SMN1; SMN2 3943/4885ALDH1A1 1041/4885 |
| US-10294203-B2 | Organic compound and electronic device comprising an organic layer comprising the organic compound | OR10J3, OCIAD2, OCIAD1 | LMNA 2565/4885SMN1; SMN2 3943/4885ALDH1A1 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.