Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367385 | 0.98 | POLB (0.62) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL11521612 | 0.95 | POLB (0.58) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL6201780 | 0.88 | LMNA (0.65) | KMT2ARAB9AMEN1MGAMGAA | |
| SCHEMBL29110346 | 0.84 | POLB (0.78) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29110265 | 0.84 | KMT2A (0.60) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29110155 | 0.84 | SMN1; SMN2 (0.53) | POLBKMT2ARAB9AMEN1L3MBTL1 | |
| SCHEMBL29110188 | 0.84 | POLB (0.61) | POLBKMT2AMEN1MGAMGAA | |
| SCHEMBL28996266 | 0.83 | LMNA (0.49) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29110194 | 0.83 | L3MBTL1 (0.71) | POLBNPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29110252 | 0.83 | APAF1 (0.50) | POLBNPC1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677443-A | Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation | 中国科学院理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |