Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200416 | 0.92 | MAPT (0.47) | SMN1; SMN2TP53ALDH1A1KDM4EMCL1 | |
| SCHEMBL6202194 | 0.88 | TP53 (0.46) | SMN1; SMN2TP53KLKB1ALDH1A1RXFP1 | |
| SCHEMBL6201979 | 0.86 | MCL1 (0.52) | TP53ALDH1A1KDM4EMCL1LMNA | |
| SCHEMBL6199567 | 0.86 | MCL1 (0.44) | KLKB1MCL1LMNACA2 | |
| SCHEMBL6202849 | 0.83 | KMT2A (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL6197449 | 0.82 | MCL1 (0.48) | ALDH1A1KDM4EMCL1NPSR1LMNA | |
| SCHEMBL6200211 | 0.82 | MCL1 (0.48) | ALDH1A1KDM4EMCL1LMNACA2 | |
| SCHEMBL6198581 | 0.82 | MCL1 (0.48) | TP53ALDH1A1KDM4EMCL1LMNA | |
| SCHEMBL6201217 | 0.82 | MCL1 (0.47) | ALDH1A1MCL1LMNA | |
| SCHEMBL6199967 | 0.82 | CCR1 (0.46) | MCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |