Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198294 | 0.90 | MGAM (0.53) | KMT2AMEN1MAPTPTGS2ALDH1A1 | |
| SCHEMBL6200106 | 0.89 | KMT2A (0.51) | KMT2AMEN1HTR2AMAPTSMN1; SMN2 | |
| SCHEMBL6200416 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6201656 | 0.83 | MCL1 (0.44) | KMT2AMEN1MAPT | |
| SCHEMBL6202196 | 0.83 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6200333 | 0.81 | MCL1 (0.48) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6198666 | 0.81 | MCL1 (0.42) | KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL6199253 | 0.80 | MCL1 (0.44) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6199074 | 0.80 | MCL1 (0.44) | ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL6202650 | 0.80 | MCL1 (0.39) | KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |