Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202215 | 0.91 | MCL1 (0.42) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6201979 | 0.90 | MCL1 (0.52) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6200550 | 0.89 | MCL1 (0.44) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6196113 | 0.88 | MCL1 (0.47) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6199967 | 0.88 | CCR1 (0.46) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6200195 | 0.87 | MCL1 (0.43) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6201656 | 0.87 | MCL1 (0.44) | MCL1LMNATUBBEGLN1NR3C1 | |
| SCHEMBL6199074 | 0.87 | MCL1 (0.44) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6199253 | 0.87 | MCL1 (0.44) | MCL1LMNACNR2TUBBEGLN1 | |
| SCHEMBL6200046 | 0.86 | TUBB (0.42) | MCL1LMNACNR2TUBBEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |