Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201979 | 0.89 | MCL1 (0.52) | MCL1TUBBEGLN1HPGDCNR2 | |
| SCHEMBL6202255 | 0.88 | MCL1 (0.44) | MCL1TUBBEGLN1HPGDCNR2 | |
| SCHEMBL6202215 | 0.88 | MCL1 (0.42) | MCL1TUBBEGLN1HPGDCNR2 | |
| SCHEMBL6200333 | 0.88 | MCL1 (0.48) | MCL1TUBBEGLN1KCNA5CNR2 | |
| SCHEMBL6196107 | 0.87 | TUBB (0.46) | MCL1TUBBEGLN1KCNA5HPGD | |
| SCHEMBL6199190 | 0.86 | MCL1 (0.47) | MCL1TUBBEGLN1KCNA5CNR2 | |
| SCHEMBL6199253 | 0.85 | MCL1 (0.44) | MCL1TUBBEGLN1HPGDCNR2 | |
| SCHEMBL6199074 | 0.85 | MCL1 (0.44) | MCL1TUBBEGLN1HPGDCNR2 | |
| SCHEMBL6201656 | 0.85 | MCL1 (0.44) | MCL1TUBBEGLN1TP53LMNA | |
| SCHEMBL6202619 | 0.85 | MCL1 (0.46) | MCL1TUBBEGLN1KCNA5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |