SCHEMBL6202288

SCHEMBL6202288

CN1CCCN(C(=O)[C@@H]2CCCN2)CC1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.58
LMNA P02545 1/20 0.57
DPP4 P27487 5/20 0.53
DPP8 Q6V1X1 4/20 0.53
DPP9 Q86TI2 4/20 0.53
FAP Q12884 1/20 0.44
DPP7 Q9UHL4 1/20 0.44
HRH2 P25021 1/20 0.43
HRH1 P35367 1/20 0.43
TGM2 P21980 1/20 0.41
KMT2A Q03164 1/20 0.39
CHRM3 P20309 1/20 0.39
PPP5C P53041 2/20 0.39
PPP2CA P67775 1/20 0.39
TFPI2 P48307 1/20 0.39
NPY4R P50391 1/20 0.39
PARP1 P09874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14123972 1.00 HTT (0.58) HTTLMNADPP4DPP8DPP9
SCHEMBL3832732 0.95 DPP4 (0.57) HTTLMNADPP4DPP8DPP9
SCHEMBL3331935 0.95 DPP4 (0.57) HTTLMNADPP4DPP8DPP9
SCHEMBL3331942 0.95 DPP4 (0.57) HTTLMNADPP4DPP8DPP9
SCHEMBL24322604 0.90 LMNA (0.51) HTTLMNADPP4DPP8DPP9
SCHEMBL18390884 0.90 LMNA (0.51) HTTLMNADPP4DPP8DPP9
SCHEMBL3332858 0.88 DPP4 (0.64) DPP4DPP8DPP9FAPDPP7
SCHEMBL3332865 0.88 DPP4 (0.64) DPP4DPP8DPP9FAPDPP7
SCHEMBL16134880 0.86 HTT (0.50) HTTLMNADPP4DPP8DPP9
SCHEMBL21552116 0.86 DPP4 (0.66) DPP4DPP8DPP9FAPDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399436-B1 OXYTOCIN AGONISTS FERRING BV (NL) 2005-03-16 EP disclosed
US-20040235753-A1 Oxytocin agonists PITT GRAY ROBERT WILLIAM (GB) 2004-11-25 US disclosed
EP-1399436-A2 OXYTOCIN AGONISTS Ferring BV (NL) 2004-03-24 EP disclosed
WO-2003000692-A2 OXYTOCIN AGONISTS FERRING BV (NL) 2003-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235753-A1 Oxytocin agonists OXTR, GNRHR, PRLHR HTT 2958/4885LMNA 3333/4885DPP4 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.