Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200655 | 0.88 | KCNH2 (0.48) | RXFP1KCNH2ALDH1A1POLA1TP53 | |
| SCHEMBL6733213 | 0.84 | ALDH1A1 (0.51) | RXFP1KCNH2ALDH1A1POLA1TP53 | |
| SCHEMBL6202284 | 0.83 | EGLN1 (0.54) | ALDH1A1POLA1EGLN1 | |
| SCHEMBL6726994 | 0.83 | KCNH2 (0.55) | RXFP1KCNH2ALDH1A1POLA1MLLT1 | |
| SCHEMBL6200011 | 0.83 | KCNH2 (0.53) | RXFP1KCNH2ALDH1A1POLA1TP53 | |
| SCHEMBL6770778 | 0.83 | KCNH2 (0.53) | RXFP1KCNH2ALDH1A1POLA1MLLT1 | |
| SCHEMBL6201283 | 0.82 | KCNH2 (0.54) | RXFP1KCNH2ALDH1A1POLA1MLLT1 | |
| SCHEMBL6692811 | 0.82 | KCNH2 (0.51) | RXFP1KCNH2ALDH1A1POLA1 | |
| SCHEMBL6606941 | 0.81 | POLA1 (0.53) | RXFP1KCNH2ALDH1A1POLA1MLLT1 | |
| SCHEMBL6198755 | 0.81 | POLA1 (0.57) | ALDH1A1POLA1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |