Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200333 | 0.90 | MCL1 (0.48) | MCL1ALDH1A1TUBBSGMS1EGLN1 | |
| SCHEMBL6199190 | 0.88 | MCL1 (0.47) | MCL1ALDH1A1GAATUBBSGMS1 | |
| SCHEMBL6200751 | 0.88 | MCL1 (0.41) | MCL1ALDH1A1HPGDTUBBPTGER4 | |
| SCHEMBL6199074 | 0.88 | MCL1 (0.44) | MCL1ALDH1A1HPGDTUBBPTGER4 | |
| SCHEMBL6199253 | 0.88 | MCL1 (0.44) | MCL1ALDH1A1HPGDTUBBPTGER4 | |
| SCHEMBL6201656 | 0.88 | MCL1 (0.44) | MCL1TUBBSGMS1PTGER4PTGER2 | |
| SCHEMBL6201979 | 0.87 | MCL1 (0.52) | MCL1ALDH1A1HPGDTUBBPTGER4 | |
| SCHEMBL6199613 | 0.87 | TUBB (0.45) | MCL1ALDH1A1HTTGAAHPGD | |
| SCHEMBL6202413 | 0.87 | MCL1 (0.43) | MCL1ALDH1A1HPGDTUBBPTGER4 | |
| SCHEMBL6196113 | 0.85 | MCL1 (0.47) | MCL1ALDH1A1HTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |