SCHEMBL62027

SCHEMBL62027

O=C=Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.52
NOS1 P29475 4/20 0.50
TSHR P16473 2/20 0.48
CYP3A4 P08684 1/20 0.48
ALDH1A1 P00352 5/20 0.46
ACHE P22303 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NOS3 P29474 2/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CES1 P23141 1/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1124777 0.94 CA12 (0.47) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL4266913 0.94 ALDH1A1 (0.51) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL21630438 0.94 PLAU (0.47) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL4266917 0.94 ALDH1A1 (0.51) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL8163344 0.92 ALDH1A1 (0.54) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL11593921 0.89 HSPB1 (0.56) PLAUNOS1ALDH1A1LMNASMN1; SMN2
SCHEMBL9357905 0.89 APP (0.55) PLAUALDH1A1SMN1; SMN2MEN1MAPT
SCHEMBL11221931 0.89 HPGD (0.58) PLAUNOS1ALDH1A1HSD17B10SMN1; SMN2
SCHEMBL9557695 0.89 MAPT (0.51) PLAUNOS1TSHRCYP3A4ALDH1A1
SCHEMBL9357909 0.89 APP (0.55) PLAUALDH1A1SMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2145 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509547-B2 Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component BASF SE (DE) 2025-12-30 US claimed
CN-115515998-B Synthesis of polyurethanes by chain growth copolymerization 伊夫·雅努 2025-06-24 CN claimed
CN-119819277-B Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-05-27 CN claimed
CN-119819277-A Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-04-15 CN claimed
CN-119120934-A Method for extracting rubidium cesium salt from environment-friendly lepidolite lithium precipitation mother solution 萍乡市拓源实业有限公司 2024-12-13 CN claimed
CN-115960017-B Modified acrylic ester monomer and photo-curable resin thereof 上海华峰龙湾技术有限公司 2024-11-22 CN claimed
CN-114878620-B Nuclear magnetic resonance-based inorganic sulfur content detection method 华东师范大学 2024-10-22 CN claimed
CN-117964892-A Modified macromer, preparation method thereof and application thereof in polymer polyol 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-114527220-B Quantitative method for trace silicon hydroxyl in organosilicon raw rubber 杭州师范大学 2023-11-17 CN claimed
US-20230348657-A1 SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT BASF SE (DE) 2023-11-02 US claimed
EP-0513541-A2 Process for the preparation of iodoalkynyl carbamates MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-11-19 EP claimed
US-5135829-A Pretreatment of indium oxide with hydroxyl, amino, or ether group containing compound RICOH COMPANY, LTD. (JP) 1992-08-04 US claimed
US-5041670-A Preparation of n-aryl amines from isocyanates DREXEL UNIVERSITY (US) 1991-08-20 US claimed
US-4946766-A Electrophotographic photoconductor having intermediate layer comprising indium oxide RICOH COMPANY, LTD. (JP) 1990-08-07 US claimed
US-4918148-A IMPROVED FLOWABILITY, MOLD RELEASE AND-OR NOTCHED IMPACT STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 1990-04-17 US claimed
EP-0159388-A2 Preparation of nuclear chlorinated compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1985-10-30 EP claimed
US-4470930-A Preparation of nuclear chlorinated aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-11 US claimed
US-4362769-A Method of neutralizing the corrosive surface of amine-cured epoxy resins THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1982-12-07 US claimed
US-3947412-A CYCLIZATION IN THE PRESENCE OF HEAVY METALS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 US claimed