Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516538 | 0.70 | PLCG1 (0.33) | PLCG1 | |
| SCHEMBL4573738 | 0.66 | LMNA (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL18283000 | 0.64 | TYMS (0.40) | — | |
| SCHEMBL8321939 | 0.64 | LMNA (0.41) | LMNASMN1; SMN2 | |
| SCHEMBL31026226 | 0.63 | CA12 (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL15473878 | 0.63 | YTHDC1 (0.31) | — | |
| SCHEMBL10647312 | 0.63 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL9627425 | 0.62 | LMNA (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL7753780 | 0.62 | LMNA (0.52) | LMNASMN1; SMN2 | |
| Formamide SCHEMBL28937217 | 0.61 | AKT1 (0.33) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432714-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1432714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003029209-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |