Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200080 | 0.77 | GABRA1 (0.55) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL2692579 | 0.76 | CA12 (0.59) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL29629010 | 0.76 | PTGS2 (0.58) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL20545862 | 0.73 | CTSA (0.53) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL20545864 | 0.73 | CTSA (0.53) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL20490456 | 0.72 | HDAC4 (0.53) | GABRA1GABRB2PTPRCPTGS2CNR1 | |
| SCHEMBL404584 | 0.70 | PTGS2 (0.66) | PTPRCPTGS2CA12CA2CA9 | |
| SCHEMBL30009937 | 0.70 | PTGS2 (0.66) | PTPRCPTGS2CA12CA2CA9 | |
| SCHEMBL4091888 | 0.69 | GABRA1 (0.49) | GABRA1GABRB2PTPRCCA12CA2 | |
| SCHEMBL13774780 | 0.69 | GABRA1 (0.49) | GABRA1GABRB2PTPRCCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |