Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199818 | 0.87 | EGLN1 (0.40) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6200398 | 0.84 | EGLN1 (0.44) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6199903 | 0.84 | EGLN1 (0.42) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6200535 | 0.84 | EGLN1 (0.42) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6201231 | 0.83 | EGLN1 (0.44) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6199949 | 0.83 | LMNA (0.39) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6198175 | 0.83 | SIGMAR1 (0.47) | NR3C1LMNAPPARGALDH1A1 | |
| SCHEMBL6200953 | 0.83 | LMNA (0.45) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6201585 | 0.83 | EGLN1 (0.43) | EGLN1NR3C1LMNAPPARGGSK3B | |
| SCHEMBL6197114 | 0.82 | EGLN1 (0.44) | EGLN1NR3C1LMNAPPARGGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |