Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204147 | 0.89 | CCNE2 (0.40) | CCNE2CCNE1CDK2HTR2AHTR2C | |
| SCHEMBL6202094 | 0.89 | HTR2C (0.47) | HTR2AHTR2CSRCCRHR1 | |
| SCHEMBL6205647 | 0.88 | CDK5 (0.41) | CDK2HTR2AHTR2CSRCMAPK1 | |
| SCHEMBL6202760 | 0.85 | CDK1 (0.40) | CCNE2CCNE1CDK2NPY5RMAPK1 | |
| SCHEMBL6203247 | 0.83 | CCNE2 (0.43) | CCNE2CCNE1CDK2HTR2AHTR2C | |
| SCHEMBL6205216 | 0.82 | BRAF (0.36) | HTR2AHTR2CADORA3 | |
| SCHEMBL6204176 | 0.82 | BRAF (0.36) | HTR2AHTR2CADORA3 | |
| SCHEMBL6203207 | 0.82 | KDM4E (0.36) | CCNE2CCNE1CDK2HTR2AHTR2C | |
| SCHEMBL6203171 | 0.79 | CCNE1 (0.37) | CCNE2CCNE1CDK2 | |
| SCHEMBL6204529 | 0.79 | CCNE2 (0.44) | CCNE2CCNE1CDK2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |