Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | TACR2 | P21452 | 5/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204147 | 0.89 | CCNE2 (0.40) | HTR2CHTR2ASRCMKNK1MAPT | |
| SCHEMBL6203250 | 0.89 | CCNE2 (0.38) | HTR2CHTR2ASRCCRHR1 | |
| SCHEMBL6205647 | 0.88 | CDK5 (0.41) | HTR2CHTR2ASRCMEN1KMT2A | |
| SCHEMBL6205216 | 0.86 | BRAF (0.36) | HTR2CHTR2ALMNAHTTMEN1 | |
| SCHEMBL6204176 | 0.86 | BRAF (0.36) | HTR2CHTR2ALMNAMEN1KMT2A | |
| SCHEMBL6202086 | 0.84 | HTR2C (0.48) | HTR2CHTR2AMAPTLMNAPOLB | |
| SCHEMBL6203207 | 0.84 | KDM4E (0.36) | HTR2CHTR2A | |
| SCHEMBL6205187 | 0.80 | HTR2C (0.42) | HTR2CHTR2ATACR2SRCCRHR1 | |
| SCHEMBL6202760 | 0.77 | CDK1 (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL6204719 | 0.74 | PGK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |