Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445582 | 0.84 | BCDIN3D (0.50) | CDK1CDK5BCDIN3D | |
| SCHEMBL3445000 | 0.84 | CDK2 (0.47) | CDK1CDK5BCDIN3D | |
| SCHEMBL3444366 | 0.81 | CDK2 (0.54) | KMT2AALDH1A1CDK1CCNB2CCNB1 | |
| SCHEMBL3444370 | 0.81 | CDK2 (0.54) | KMT2AALDH1A1CDK1CCNB2CCNB1 | |
| SCHEMBL3445110 | 0.81 | CDK2 (0.55) | ALDH1A1LMNASMN1; SMN2CDK1CCNB2 | |
| SCHEMBL6226169 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL3445180 | 0.80 | CCNE1 (0.55) | CDK5 | |
| SCHEMBL6201910 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL3445887 | 0.79 | CDK2 (0.53) | CDK1CCNB1CDK5RAB9ABCDIN3D | |
| SCHEMBL6203832 | 0.76 | KMT2A (0.46) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |