Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE6C | P51160 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201113 | 0.84 | CDK1 (0.46) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL6205622 | 0.82 | CCNE2 (0.35) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL6202735 | 0.81 | CCNE1 (0.44) | CDK2CCNE2CCNE1 | |
| SCHEMBL6203391 | 0.80 | CCNE2 (0.31) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL3444131 | 0.80 | CDK1 (0.46) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL6205419 | 0.78 | CCNE1 (0.36) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL3444674 | 0.78 | CDK2 (0.42) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL3445521 | 0.78 | CDK2 (0.37) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL3444730 | 0.77 | CDK2 (0.47) | CDK1CDK5CDK2CCNE2CCNE1 | |
| SCHEMBL6202208 | 0.77 | CDK1 (0.33) | CDK1CDK5CDK2CCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |