Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739158 | 0.85 | RAB9A (0.59) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL3807595 | 0.83 | NPC1 (0.44) | ALDH1A1ADRA2BPTGS1TDP1NPC1 | |
| SCHEMBL2418152 | 0.81 | CYP1A2 (0.44) | ALDH1A1ADRA2BPTGS1TDP1NPC1 | |
| SCHEMBL621074 | 0.81 | NPC1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1NPC1 | |
| SCHEMBL30076288 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL19713015 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL9131541 | 0.80 | CYP1A2 (0.53) | ALDH1A1ADRA2BPTGS1TDP1NPC1 | |
| SCHEMBL31060373 | 0.80 | AR (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL620881 | 0.79 | MCHR1 (0.42) | ALDH1A1ADRA2BPTGS1TDP1NPC1 | |
| SCHEMBL2416172 | 0.79 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583852-B2 | Heterocycle derivative | JW PHARMACEUTICAL CORPORATION (KR) | 2026-03-24 | — | — | US | disclosed |
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-116102495-B | 1,2,3, 4-Tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-20240190828-A1 | Small Molecule Inhibitors of PBRM1-BD2 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-13 | — | — | US | disclosed |
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-4291195-A1 | SMALL MOLECULE INHIBITORS OF PBRM1-BD2 | The Medical College of Wisconsin, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116969921-A | Compound for inhibiting or degrading HPK1 kinase and application thereof in medicine | 四川海思科制药有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116102495-A | 1,2,3, 4-tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2023-05-12 | — | — | CN | disclosed |
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| US-4404230-A | ARTICIFIAL SWEETENERS | DR. KARL THOMAE GMBH (DE) | 1983-09-13 | — | — | US | disclosed |
| EP-0065811-A1 | Disperse azopyrimidine dyestuffs | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |
| EP-0038458-A1 | 4-Hydroxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide, their salts, their preparation and their utilization | Dr. Karl Thomae GmbH (DE) | 1981-10-28 | — | — | EP | disclosed |
| US-4160100-A | OXAMIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4054666-A | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054657-A | Pyrimidinyl oxamic acids and esters, and compositions and methods for the suppression of allergic manifestations | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054661-A | Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4036837-A | 2 Alkoxyoxamoyl-pyrazines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3987192-A | ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3966965-A | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190828-A1 | Small Molecule Inhibitors of PBRM1-BD2 | BRD2, PBRM1, BRDT | ALDH1A1 4514/4885ADRA2B 2655/4885PTGS1 2551/4885 |
| US-12583852-B2 | Heterocycle derivative | AR, SRD5A1, NR5A1 | ALDH1A1 1733/4885ADRA2B 4126/4885PTGS1 1407/4885 |
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | ALDH1A1 597/4885ADRA2B 245/4885PTGS1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.