Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204318 | 1.00 | RAB9A (0.73) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL825926 | 0.92 | RAB9A (0.84) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL12181432 | 0.85 | RAB9A (0.90) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL3456092 | 0.84 | RAB9A (1.00) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL12181229 | 0.84 | RAB9A (1.00) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL359241 | 0.83 | RAB9A (0.74) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL12858327 | 0.77 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL27876089 | 0.77 | RAB9A (0.66) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL14568945 | 0.75 | TSHR (0.60) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL10827784 | 0.75 | RAB9A (0.58) | RAB9ANPC1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595871-A2 | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases | NPS PHARMACEUTICALS, INC. (US) | 2005-11-16 | — | — | EP | disclosed |