Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335602 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL457758 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL11632629 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL27416167 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL7290800 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRTDP1SNCA | |
| SCHEMBL29141200 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL27892168 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRPOLBSNCA | |
| SCHEMBL8927043 | 0.77 | ALDH1A1 (0.37) | ALDH1A1HPGDTSHRTDP1MEN1 | |
| SCHEMBL13835837 | 0.77 | CYP1A2 (0.51) | ALDH1A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL57882 | 0.76 | TSHR (0.40) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100393705-C | Developer component and use thereof for dyeing keratin fibres | HENKEL KGAA (DE) | 2008-06-11 | — | — | CN | disclosed |
| EP-1507776-A1 | 2-OXO-1,3,4-TRIHYDROQUINAZOLINYL DERIVATIVES FOR THE TREATMENT OF CELL PROLIFERATION-RELATED DISORDERS | Amgen Inc. (US) | 2005-02-23 | — | — | EP | disclosed |
| CN-1578771-A | Developer components and their use for dyeing keratinic fibers | HENKEL KGAA (DE) | 2005-02-09 | — | — | CN | disclosed |
| WO-2003101985-A1 | 2-OXO-1,3,4-TRIHYDROQUINAZOLINYL DERIVATIVES FOR THE TREATMENT OF CELL PROLIFERATION-RELATED DISORDERS | AMGEN INC. (US) | 2003-12-11 | — | — | WO | disclosed |