SCHEMBL8927043

SCHEMBL8927043

C=CCc1c[c]ccc1[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
HCAR3 P49019 1/20 0.35
POLB P06746 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28277263 0.87 POLB (0.36) ALDH1A1HPGDTSHRGABRA1GABRB2
SCHEMBL3335602 0.80 ALDH1A1 (0.42) ALDH1A1HPGDTSHRPOLBTDP1
SCHEMBL457758 0.79 ALDH1A1 (0.41) ALDH1A1HPGDTSHRPOLBTDP1
SCHEMBL7290800 0.77 ALDH1A1 (0.43) ALDH1A1HPGDTSHRTDP1L3MBTL1
SCHEMBL11632629 0.77 ALDH1A1 (0.56) ALDH1A1HPGDTSHRTDP1MEN1
SCHEMBL27416167 0.77 ALDH1A1 (0.40) ALDH1A1HPGDTSHRPOLBTDP1
SCHEMBL6204415 0.77 ALDH1A1 (0.40) ALDH1A1HPGDTSHRPOLBTDP1
SCHEMBL30367918 0.75 ALDH1A1 (0.58) ALDH1A1HPGDTSHRTDP1MEN1
SCHEMBL1135905 0.75 ALDH1A1 (0.58) ALDH1A1HPGDTSHRTDP1MEN1
SCHEMBL29141200 0.75 ALDH1A1 (0.38) ALDH1A1HPGDTSHRHCAR3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102010475-B Photopolymerization initiator and photosensitive composition NIPPON STEEL & SUMIKIN CHEM CO 2015-05-20 CN disclosed
CN-102010475-A Photopolymerization initiator and photosensitive composition NIPPON STEEL CHEMICAL CO 2011-04-13 CN disclosed
US-5663371-A Process for preparing polycyclic dyes ZENECA LIMITED (GB) 1997-09-02 US disclosed
EP-0673400-A1 POLYCYCLIC DYES BASF AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
WO-1994012577-A2 POLYCYCLIC DYES ZENECA LIMITED (GB) 1994-06-09 WO disclosed