Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920116 | 0.94 | MEN1 (0.47) | MEN1KMT2AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13980904 | 0.90 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2ALOX5TDP1 | |
| SCHEMBL10410232 | 0.89 | ESR1 (0.46) | MEN1KMT2AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL1767974 | 0.87 | LMNA (0.47) | MEN1KMT2AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4206097 | 0.87 | MMP8 (0.50) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12273789 | 0.86 | LMNA (0.46) | MEN1KMT2AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL16280745 | 0.84 | MAPT (0.41) | MEN1KMT2AMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL6207003 | 0.83 | KMT2A (0.43) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL10896682 | 0.83 | POLB (0.49) | MEN1KMT2AMAPK1SMN1; SMN2PTGES | |
| SCHEMBL5699336 | 0.83 | ESR1 (0.44) | MAPK1SMN1; SMN2ALDH1A1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564200-A1 | Ketone compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| CN-1061410-A | Substituted azole, its preparation method comprises the preparation and the application thereof of substituted azole | HOECHST AG (DE) | 1992-05-27 | — | — | CN | disclosed |