Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054991 | 0.86 | MEN1 (0.58) | KMT2AMEN1LMNAKCNK3RAB9A | |
| SCHEMBL9682036 | 0.84 | MAPT (0.65) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL7745875 | 0.81 | MAPT (0.76) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL6250922 | 0.78 | MAPT (0.72) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL3531261 | 0.77 | MAPT (0.70) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL850791 | 0.77 | MEN1 (1.00) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL6055167 | 0.77 | LMNA (0.70) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL5494349 | 0.76 | MAPT (0.65) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL4238475 | 0.75 | MAPT (0.64) | MAPTKMT2AMEN1LMNAKCNK3 | |
| SCHEMBL6054953 | 0.75 | NPC1 (0.69) | MAPTKMT2AMEN1LMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446381-A1 | ANTHRANILIC ACID AMIDES AND PHARMACEUTICAL USE THEREOF | Novartis AG (CH) | 2004-08-18 | — | — | EP | claimed |
| WO-2003040101-A1 | ANTHRANILIC ACID AMIDES AND PHARMACEUTICAL USE THEREOF | NOVARTIS AG (CH) | 2003-05-15 | — | — | WO | claimed |
| EP-1572686-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | Novartis AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| EP-1446382-A1 | ANTHRANILIC ACID AMIDES AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| WO-2004052884-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVARTIS AG (CH) | 2004-06-24 | — | — | WO | disclosed |
| WO-2003040102-A1 | ANTHRANILIC ACID AMIDES AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2003-05-15 | — | — | WO | disclosed |