Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.49 |
| ▸ | CPT1A | P50416 | 1/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204555 | 1.00 | PGR (0.59) | PGRALDH1A1SMN1; SMN2PFKFB3MEN1 | |
| SCHEMBL6204559 | 1.00 | PGR (0.59) | PGRALDH1A1SMN1; SMN2PFKFB3MEN1 | |
| SCHEMBL6205517 | 0.92 | MEN1 (0.49) | PGRALDH1A1PFKFB3MEN1KMT2A | |
| SCHEMBL6205183 | 0.92 | MEN1 (0.49) | PGRALDH1A1PFKFB3MEN1KMT2A | |
| SCHEMBL6205518 | 0.92 | MEN1 (0.49) | PGRALDH1A1PFKFB3MEN1KMT2A | |
| SCHEMBL6205252 | 0.87 | KMT2A (0.59) | PGRPFKFB3MEN1KMT2APOLB | |
| SCHEMBL6205255 | 0.87 | KMT2A (0.59) | PGRPFKFB3MEN1KMT2APOLB | |
| SCHEMBL6205259 | 0.87 | KMT2A (0.59) | PGRPFKFB3MEN1KMT2APOLB | |
| SCHEMBL6206300 | 0.86 | MEN1 (0.53) | ALDH1A1PFKFB3MEN1KMT2ATSHR | |
| SCHEMBL6204582 | 0.86 | MEN1 (0.53) | ALDH1A1PFKFB3MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |