Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ITGA1 | P56199 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205517 | 1.00 | MEN1 (0.49) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6205518 | 1.00 | MEN1 (0.49) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204559 | 0.92 | PGR (0.59) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204555 | 0.92 | PGR (0.59) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204561 | 0.92 | PGR (0.59) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204122 | 0.87 | ITGA1 (0.50) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204114 | 0.87 | ITGA1 (0.50) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6204118 | 0.87 | ITGA1 (0.50) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6205252 | 0.86 | KMT2A (0.59) | MEN1KMT2APOLBPGRPFKFB3 | |
| SCHEMBL6205255 | 0.86 | KMT2A (0.59) | MEN1KMT2APOLBPGRPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |