Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204562 | 1.00 | AKR1C3 (0.61) | AKR1C3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6204571 | 1.00 | AKR1C3 (0.61) | AKR1C3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7311403 | 0.84 | AKR1C3 (0.85) | AKR1C3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6205259 | 0.84 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBPFKFB3 | |
| SCHEMBL6205252 | 0.84 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBPFKFB3 | |
| SCHEMBL6205255 | 0.84 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBPFKFB3 | |
| SCHEMBL6204561 | 0.82 | PGR (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6204559 | 0.82 | PGR (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6204555 | 0.82 | PGR (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6206726 | 0.81 | TSHR (0.57) | ALDH1A1PFKFB3MAPTITGA1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |