Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 7/20 | 0.37 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22982234 | 0.73 | MEN1 (0.35) | GAALMNAMAOAMAOBKDM1A | |
| SCHEMBL23927554 | 0.71 | MAOA (0.40) | LMNAMAOAMAOBKDM1AHPGD | |
| SCHEMBL8312339 | 0.70 | MAOA (0.45) | GAAMAOAMAOBKDM1ATP53 | |
| SCHEMBL10775573 | 0.68 | ALDH1A1 (0.43) | GAALMNAKDM1AALDH1A1TSHR | |
| SCHEMBL18396745 | 0.66 | CREBBP (0.39) | LMNAMAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL2374703 | 0.65 | MAOA (0.54) | GAAMAOAMAOBKDM1ATP53 | |
| SCHEMBL17063291 | 0.65 | MEN1 (0.41) | GAAGBA1TSHR | |
| SCHEMBL1558534 | 0.65 | GBA1 (0.48) | GAALMNAKDM1AGBA1ALDH1A1 | |
| SCHEMBL14828724 | 0.63 | MAOA (0.42) | MAOAMAOBKDM1AALDH1A1TSHR | |
| SCHEMBL11369040 | 0.63 | OPRL1 (0.45) | GAALMNAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549278-A4 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1549278-A2 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004012684-A2 | M3MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |