Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19027642 | 0.82 | ACP3 (0.44) | AOC3ACP3SLC6A4SLC6A2TSHR | |
| SCHEMBL6203322 | 0.79 | AOC3 (0.53) | AOC3ACP3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23956426 | 0.79 | SLC6A4 (0.44) | AOC3ACP3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6205146 | 0.79 | CNR2 (0.39) | AOC3TSHR | |
| SCHEMBL3096347 | 0.78 | AOC3 (0.56) | AOC3ACP3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6201854 | 0.78 | AOC3 (0.49) | AOC3ACP3 | |
| SCHEMBL13140614 | 0.78 | HDAC4 (0.47) | AOC3TSHRADRB1 | |
| SCHEMBL28582936 | 0.78 | CYP3A4 (0.47) | AOC3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6204449 | 0.78 | ADRB1 (0.53) | SLC6A3TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL11395224 | 0.78 | AOC3 (0.51) | AOC3ACP3SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |