Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204860 | 0.80 | TSHR (0.47) | TAAR1 | |
| SCHEMBL5761123 | 0.75 | IDO1 (0.47) | SLC1A1IDO1AGXTPPARGPPARA | |
| SCHEMBL23283605 | 0.74 | TAAR1 (0.47) | SLC1A1IDO1AGXTPPARGPPARA | |
| SCHEMBL10294624 | 0.74 | IDO1 (0.60) | IDO1AGXTTAAR1HCAR2MAOB | |
| SCHEMBL6203525 | 0.74 | AOC3 (0.41) | IDO1 | |
| SCHEMBL6204382 | 0.73 | SLC1A1 (0.46) | SLC1A1IDO1AGXTPPARGPPARA | |
| SCHEMBL5475645 | 0.72 | MMP8 (0.52) | SLC1A1PPARGPPARAHCAR2MAOB | |
| SCHEMBL25482996 | 0.71 | TAAR1 (0.44) | SLC1A1IDO1AGXTPPARGPPARA | |
| SCHEMBL6201896 | 0.71 | IDO1 (0.38) | IDO1PPARGPPARATAAR1MAOB | |
| SCHEMBL23811004 | 0.71 | TAAR1 (0.45) | SLC1A1IDO1AGXTTAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |