Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202381 | 0.80 | SLC6A2 (0.41) | IDO1ALDH1A1PPARGPPARATAAR1 | |
| SCHEMBL6203702 | 0.79 | ALDH1A1 (0.42) | IDO1ALDH1A1TAAR1KMT2ACYP3A4 | |
| SCHEMBL6204860 | 0.75 | TSHR (0.47) | ALDH1A1POLBTAAR1SLC6A2SLC6A4 | |
| Ether SCHEMBL453112 | 0.73 | IDO1 (0.44) | IDO1RIPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL12874173 | 0.72 | IDO1 (0.57) | IDO1ALDH1A1KDM4EPOLBTAAR1 | |
| SCHEMBL6201417 | 0.72 | IDO1 (0.42) | IDO1ALDH1A1PPARGPPARATAAR1 | |
| SCHEMBL5761538 | 0.72 | IDO1 (0.42) | IDO1ALDH1A1KDM4EPOLBPPARG | |
| SCHEMBL6204253 | 0.70 | PPARG (0.40) | IDO1RIPK1ALDH1A1PPARGPPARA | |
| SCHEMBL6200983 | 0.70 | TAAR1 (0.46) | IDO1ALDH1A1PPARGPPARATAAR1 | |
| SCHEMBL8638253 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |