Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471067 | 0.85 | RAB9A (0.76) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25713615 | 0.85 | RAB9A (0.76) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30161523 | 0.81 | MAPT (1.00) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2090795 | 0.81 | MAPT (1.00) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27604182 | 0.81 | KDM4E (0.60) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5831730 | 0.80 | KDM4E (0.75) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2242816 | 0.79 | KDM4E (1.00) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5981201 | 0.79 | MAPT (0.71) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24140789 | 0.78 | KDM4E (0.76) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13053014 | 0.77 | RAB9A (0.69) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539723-A1 | NOVEL USE OF BENZOTHIAZOLE DERIVATIVES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004016600-A1 | NOVEL USE OF BENZOTHIAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | claimed |
| EP-1539723-A1 | NOVEL USE OF BENZOTHIAZOLE DERIVATIVES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004016600-A1 | NOVEL USE OF BENZOTHIAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | disclosed |