Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | LCAT | P04180 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585784 | 0.89 | ADRB2 (0.60) | ADRB2HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL5585780 | 0.89 | ADRB2 (0.60) | ADRB2HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL5585823 | 0.89 | ADRB2 (0.60) | ADRB2HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL5585598 | 0.88 | ADRB2 (0.65) | ADRB2HTR2CACVR1LCATPRKCQ | |
| SCHEMBL5585596 | 0.88 | ADRB2 (0.65) | ADRB2HTR2CACVR1LCATPRKCQ | |
| SCHEMBL5585785 | 0.88 | ADRB2 (0.65) | ADRB2HTR2CACVR1LCATPRKCQ | |
| SCHEMBL15219155 | 0.79 | HTR2C (0.48) | ADRB2HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL29388809 | 0.76 | ADRB2 (0.97) | ADRB2HTR2CHTR2ALCATCXCR3 | |
| SCHEMBL906077 | 0.76 | ADRB2 (0.97) | ADRB2HTR2CHTR2ALCATCXCR3 | |
| Hydrochloric Acid SCHEMBL5585896 | 0.75 | ADRB2 (1.00) | ADRB2HTR2CHTR2ALCATCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506185-A1 | NOVEL COMPOUNDS AND THEIR USE | Biovitrum AB (SE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097636-A1 | NOVEL COMPOUNDS AND THEIR USE | BIOVITRUM AB (SE) | 2003-11-27 | — | — | WO | disclosed |