Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207004 | 0.83 | POLB (0.70) | KDM4EHTTALDH1A1F2HSD17B10 | |
| SCHEMBL396966 | 0.82 | NPC1 (0.71) | NPC1RAB9A | |
| SCHEMBL13091203 | 0.81 | TP53 (0.70) | KDM4EALDH1A1F2HSD17B10MEN1 | |
| SCHEMBL6205660 | 0.80 | ADORA2A (0.68) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6165240 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1F2HSD17B10MEN1 | |
| SCHEMBL6207018 | 0.80 | HPGD (0.68) | KDM4EALDH1A1F2HSD17B10MEN1 | |
| SCHEMBL7742074 | 0.79 | NHERF1 (0.62) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL13091211 | 0.79 | MAPT (0.67) | KDM4EHTTALDH1A1F2HSD17B10 | |
| SCHEMBL13942929 | 0.79 | MAPT (0.75) | KDM4EALDH1A1F2HSD17B10MEN1 | |
| SCHEMBL13091173 | 0.79 | MAPT (0.75) | KDM4EHTTALDH1A1F2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |