Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CFTR | P13569 | 3/20 | 0.66 |
| ▸ | GABRP | O00591 | 1/20 | 0.64 |
| ▸ | GABRD | O14764 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.64 |
| ▸ | GABRE | P78334 | 1/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742074 | 0.91 | NHERF1 (0.62) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8251765 | 0.90 | GABRP (0.74) | ADORA2APOLBNPC1RAB9AGABRP | |
| SCHEMBL6818435 | 0.89 | POLB (0.67) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6229836 | 0.89 | CFTR (0.61) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6204753 | 0.89 | GABRP (0.67) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6204748 | 0.88 | CFTR (0.60) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18229454 | 0.88 | POLB (0.70) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6224870 | 0.87 | CFTR (0.62) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6205300 | 0.86 | CFTR (0.61) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6206312 | 0.86 | GABRP (0.69) | ADORA2APOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |