Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 15/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205626 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6207149 | 0.87 | EPHX1 (0.45) | EPHX1ALDH1A1HTTNAAAL3MBTL1 | |
| SCHEMBL6030772 | 0.86 | EPHX1 (0.46) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6030269 | 0.86 | EPHX1 (0.46) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6030406 | 0.86 | EPHX1 (0.46) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6030371 | 0.86 | EPHX1 (0.46) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6030458 | 0.81 | EPHX1 (0.48) | EPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL6208748 | 0.81 | EPHX1 (0.47) | EPHX1ALDH1A1HTTEPHX2L3MBTL1 | |
| SCHEMBL6030199 | 0.81 | EPHX1 (0.41) | EPHX1ALDH1A1HTTNAAAEPHX2 | |
| SCHEMBL6030430 | 0.81 | EPHX1 (0.41) | EPHX1ALDH1A1HTTEPHX2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |