Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030362 | 0.90 | EPHX1 (0.46) | EPHX1ALDH1A1HTTRECQLNPC1 | |
| SCHEMBL6030764 | 0.89 | EPHX1 (0.46) | EPHX1ALDH1A1HTTRECQLNPC1 | |
| SCHEMBL6205626 | 0.87 | EPHX1 (0.45) | EPHX1ALDH1A1HTTL3MBTL1NAAA | |
| SCHEMBL6205569 | 0.87 | EPHX1 (0.45) | EPHX1ALDH1A1HTTL3MBTL1NAAA | |
| SCHEMBL6030339 | 0.81 | POLB (0.42) | EPHX1ALDH1A1HTTRECQLNPC1 | |
| SCHEMBL6207152 | 0.81 | EPHX1 (0.44) | EPHX1ALDH1A1HTTNAAAKMT2A | |
| SCHEMBL6030814 | 0.80 | POLB (0.43) | EPHX1ALDH1A1HTTRECQLNPC1 | |
| SCHEMBL6208748 | 0.80 | EPHX1 (0.47) | EPHX1ALDH1A1HTTL3MBTL1HPGD | |
| SCHEMBL6030430 | 0.76 | EPHX1 (0.41) | EPHX1ALDH1A1HTTRECQLNPC1 | |
| SCHEMBL6030269 | 0.75 | EPHX1 (0.46) | EPHX1ALDH1A1HTTL3MBTL1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |