Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030484 | 0.89 | MAPT (0.48) | EPHX1ALDH1A1HTTCYP3A4TSHR | |
| SCHEMBL6030356 | 0.81 | MAPT (0.45) | EPHX1ALDH1A1HTTCYP3A4TSHR | |
| SCHEMBL6031142 | 0.81 | MAPT (0.45) | EPHX1ALDH1A1HTTCYP3A4TSHR | |
| SCHEMBL6031521 | 0.81 | MAPT (0.45) | EPHX1ALDH1A1HTTCYP3A4TSHR | |
| SCHEMBL6029684 | 0.81 | MAPT (0.45) | EPHX1ALDH1A1HTTCYP3A4TSHR | |
| SCHEMBL6205626 | 0.81 | EPHX1 (0.45) | EPHX1ALDH1A1HTTL3MBTL1EPHX2 | |
| SCHEMBL6205569 | 0.81 | EPHX1 (0.45) | EPHX1ALDH1A1HTTL3MBTL1EPHX2 | |
| SCHEMBL6030266 | 0.81 | EPHX1 (0.43) | EPHX1ALDH1A1HTTMEN1HPGD | |
| SCHEMBL6207149 | 0.80 | EPHX1 (0.45) | EPHX1ALDH1A1HTTTSHRL3MBTL1 | |
| SCHEMBL6030263 | 0.80 | EPHX1 (0.43) | EPHX1ALDH1A1HTTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |