Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206246 | 1.00 | MEN1 (0.53) | MEN1KMT2APKMLMNAPOLB | |
| SCHEMBL6206251 | 1.00 | MEN1 (0.53) | MEN1KMT2APKMLMNAPOLB | |
| SCHEMBL6205252 | 0.90 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBWDR5 | |
| SCHEMBL6205255 | 0.90 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBWDR5 | |
| SCHEMBL6205259 | 0.90 | KMT2A (0.59) | MEN1KMT2ALMNAPOLBWDR5 | |
| SCHEMBL6206300 | 0.87 | MEN1 (0.53) | MEN1KMT2APKMLMNAPOLB | |
| SCHEMBL6206304 | 0.87 | MEN1 (0.53) | MEN1KMT2APKMLMNAPOLB | |
| SCHEMBL6204582 | 0.87 | MEN1 (0.53) | MEN1KMT2APKMLMNAPOLB | |
| SCHEMBL6204503 | 0.85 | HSD17B1 (0.52) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL6205979 | 0.85 | HSD17B1 (0.52) | MEN1KMT2ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |