Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 3/20 | 0.51 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205977 | 1.00 | HSD17B1 (0.52) | HSD17B1HSD17B2WDR5ITGA1LMNA | |
| SCHEMBL6204503 | 1.00 | HSD17B1 (0.52) | HSD17B1HSD17B2WDR5ITGA1LMNA | |
| SCHEMBL6205383 | 0.91 | ITGA1 (0.53) | WDR5ITGA1LMNAPOLBNPC1 | |
| SCHEMBL6205102 | 0.91 | ITGA1 (0.53) | WDR5ITGA1LMNAPOLBNPC1 | |
| SCHEMBL6205381 | 0.91 | ITGA1 (0.53) | WDR5ITGA1LMNAPOLBNPC1 | |
| SCHEMBL6205543 | 0.86 | WDR5 (0.57) | HSD17B1HSD17B2WDR5ITGA1LMNA | |
| SCHEMBL6206630 | 0.86 | WDR5 (0.57) | HSD17B1HSD17B2WDR5ITGA1LMNA | |
| SCHEMBL6206627 | 0.86 | WDR5 (0.57) | HSD17B1HSD17B2WDR5ITGA1LMNA | |
| SCHEMBL6205747 | 0.85 | MEN1 (0.53) | WDR5LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL6206251 | 0.85 | MEN1 (0.53) | WDR5LMNAPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |