Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063107 | 0.87 | LTB4R (0.37) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4054249 | 0.86 | CYSLTR2 (0.38) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL14159613 | 0.86 | CYSLTR2 (0.38) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4056211 | 0.84 | CYSLTR2 (0.44) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4242583 | 0.84 | LTB4R (0.38) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4052827 | 0.84 | CYSLTR1 (0.39) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4230775 | 0.83 | TBXAS1 (0.39) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4228194 | 0.82 | CYSLTR2 (0.39) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL4234235 | 0.82 | CYSLTR2 (0.42) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL4229150 | 0.81 | LTB4R (0.36) | LTB4RTBXA2RTBXAS1CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560834-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004043966-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-05-27 | — | — | WO | disclosed |