Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946740 | 0.89 | ALDH1A1 (0.41) | ACACBPDE4BALDH1A1TSHRKDM4E | |
| SCHEMBL3941671 | 0.87 | ALDH1A1 (0.41) | ACACBPDE4BALDH1A1TSHRKDM4E | |
| SCHEMBL5747442 | 0.81 | ALDH1A1 (0.39) | ACACBPDE4BALDH1A1TSHRKDM4E | |
| SCHEMBL5225656 | 0.80 | ALDH1A1 (0.50) | ACACBALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL5746990 | 0.79 | ALDH1A1 (0.37) | ACACBPDE4BALDH1A1TSHRKDM4E | |
| SCHEMBL3941664 | 0.71 | ACACB (0.42) | ACACBPDE4BL3MBTL1PDE4APDE4C | |
| SCHEMBL5746874 | 0.70 | ALDH1A1 (0.47) | PDE4BALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL15895661 | 0.69 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL3952203 | 0.68 | ACACB (0.40) | ACACBPDE4BALDH1A1MAPTMAPK1 | |
| SCHEMBL3941652 | 0.68 | ACACB (0.44) | ACACBPDE4BALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981517-B1 | PREPARATION OF FUSED POLYCYCLIC ALKALOIDS BY RING CLOSURE OF AZOMETHINE YLIDES | UNIV AUSTRALIAN (AU) | 2005-11-16 | — | — | EP | disclosed |