Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.47 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.47 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750448 | 0.94 | PYGL (0.49) | IP6K1IP6K3IP6K2SMN1; SMN2NPSR1 | |
| SCHEMBL2915188 | 0.81 | PTPN1 (0.49) | IP6K1IP6K3IP6K2SMN1; SMN2LMNA | |
| SCHEMBL1749404 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTNPSR1PYGLHPGD | |
| SCHEMBL1749350 | 0.79 | PTPN1 (0.69) | IP6K1IP6K3IP6K2SMN1; SMN2LMNA | |
| SCHEMBL694058 | 0.78 | PTPN1 (0.72) | IP6K1IP6K3IP6K2SMN1; SMN2LMNA | |
| SCHEMBL11732553 | 0.78 | PTPN1 (0.72) | IP6K1IP6K3IP6K2SMN1; SMN2LMNA | |
| SCHEMBL4604019 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMAPTNPSR1HPGD | |
| SCHEMBL2907510 | 0.76 | F11 (0.48) | SMN1; SMN2MAPTEPHX2FAAH | |
| SCHEMBL11729220 | 0.76 | PTPN1 (0.64) | IP6K1IP6K3IP6K2SMN1; SMN2LMNA | |
| SCHEMBL18960368 | 0.75 | EPHX2 (0.64) | SMN1; SMN2LMNAMAPTNPSR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597228-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004072025-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |