Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206005 | 1.00 | FFAR1 (0.49) | FFAR1SPHK2ALKBH1SPHK1ALDH1A1 | |
| SCHEMBL6205999 | 1.00 | FFAR1 (0.49) | FFAR1SPHK2ALKBH1SPHK1ALDH1A1 | |
| SCHEMBL6206165 | 0.87 | SPHK2 (0.50) | FFAR1SPHK2ALKBH1SPHK1ALDH1A1 | |
| SCHEMBL6206166 | 0.87 | SPHK2 (0.50) | FFAR1SPHK2ALKBH1SPHK1ALDH1A1 | |
| SCHEMBL6206160 | 0.87 | SPHK2 (0.50) | FFAR1SPHK2ALKBH1SPHK1ALDH1A1 | |
| SCHEMBL6204938 | 0.84 | MRGPRX4 (0.42) | SPHK2SPHK1ALDH1A1NPC1RAB9A | |
| SCHEMBL6207013 | 0.84 | MRGPRX4 (0.42) | SPHK2SPHK1ALDH1A1NPC1RAB9A | |
| SCHEMBL6207009 | 0.84 | MRGPRX4 (0.42) | SPHK2SPHK1ALDH1A1NPC1RAB9A | |
| SCHEMBL6947812 | 0.82 | MEN1 (0.56) | ALDH1A1MAOBGPBAR1PTPN1KDM4E | |
| SCHEMBL6947809 | 0.82 | MEN1 (0.56) | ALDH1A1MAOBGPBAR1PTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |