Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821817 | 0.84 | PPARA (0.35) | — | |
| SCHEMBL7655000 | 0.74 | HSD11B1 (0.36) | ACACBACACA | |
| SCHEMBL14709918 | 0.72 | ACACB (0.33) | ACACBACACA | |
| SCHEMBL5954975 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL2163672 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL10153351 | 0.68 | HSD11B1 (0.31) | ACACBACACA | |
| SCHEMBL6124859 | 0.65 | — | — | |
| SCHEMBL5616028 | 0.64 | ALDH1A1 (0.39) | — | |
| SCHEMBL10094578 | 0.63 | NPC1 (0.41) | — | |
| SCHEMBL23591981 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515726-A1 | MORPHOLINE AND TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004002491-A1 | MORPHOLINE AND TETRAHYDROPYRAN DRIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2004-01-08 | — | — | WO | disclosed |