Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304556 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL10175659 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL14768876 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| Hydrochloric Acid SCHEMBL605634 | 0.84 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL2062221 | 0.82 | LOXL2 (0.55) | ALDH1A1TDP1TSHRCYP3A4LOXL2 | |
| SCHEMBL502546 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL14097760 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL29796062 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL30780892 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4KAT2B | |
| SCHEMBL694999 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738798-A | Indole derivatives as somatostatin agonists or antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |