Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018459 | 0.87 | NAPRT (0.61) | MAPTNAPRTHSD17B10HDAC3HDAC4 | |
| SCHEMBL27538195 | 0.81 | EPHX2 (0.63) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL7745292 | 0.80 | MAPT (0.71) | MAPTNAPRTHSD17B10HDAC3HDAC4 | |
| SCHEMBL5804865 | 0.78 | MAPT (0.65) | MAPTNAPRTHSD17B10HDAC3HDAC4 | |
| SCHEMBL14914 | 0.77 | MAPT (0.85) | MAPTNAPRTHSD17B10POLBKDM1A | |
| SCHEMBL9121361 | 0.77 | MAPT (0.85) | MAPTNAPRTHSD17B10POLBKDM1A | |
| SCHEMBL3021545 | 0.77 | MAPT (0.67) | MAPTNAPRTHSD17B10HDAC3HDAC4 | |
| SCHEMBL9222067 | 0.77 | SMN1; SMN2 (0.59) | MAPTNAPRTHSD17B10HDAC3HDAC4 | |
| SCHEMBL1689206 | 0.77 | EPHX2 (0.68) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Acetanilide SCHEMBL9260422 | 0.77 | MAPT (0.77) | MAPTNAPRTHSD17B10POLBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780533-A | REACTION PRODUCT OF TETRAZO COMPOUND OF 3,3'-DICHLOROBENZIDINE AND ACETOANILIDE DERIVATIVE | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1988-10-25 | — | — | US | claimed |
| EP-1047672-B1 | PROCESS FOR PREPARING SPARINGLY SOLUBLE AROMATIC AMINES | CIBA SC HOLDING AG (CH) | 2005-06-22 | — | — | EP | disclosed |
| EP-1047672-A1 | PROCESS FOR PREPARING SPARINGLY SOLUBLE AROMATIC AMINES | Ciba SC Holding AG (CH) | 2000-11-02 | — | — | EP | disclosed |
| US-6087480-A | Process for preparing sparingly soluble aromatic amines | CIBA SPECIALTY CHEMCALS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| WO-1999036402-A1 | PROCESS FOR PREPARING SPARINGLY SOLUBLE AROMATIC AMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-07-22 | — | — | WO | disclosed |
| US-4780533-A | REACTION PRODUCT OF TETRAZO COMPOUND OF 3,3'-DICHLOROBENZIDINE AND ACETOANILIDE DERIVATIVE | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1988-10-25 | — | — | US | disclosed |