Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967437 | 1.00 | TLR9 (0.40) | TLR9CTRB1CES2FASNLMNA | |
| SCHEMBL11741164 | 0.86 | LTA4H (0.41) | LMNA | |
| SCHEMBL11737987 | 0.84 | NOTUM (0.39) | LMNAGAA | |
| SCHEMBL11454739 | 0.82 | FASN (0.41) | FASN | |
| SCHEMBL11739217 | 0.82 | GAA (0.40) | CES2LMNAGAAMDM2 | |
| SCHEMBL11740374 | 0.82 | MDM2 (0.38) | LMNAGAAMAOBGRM2MDM2 | |
| SCHEMBL11741970 | 0.82 | MDM2 (0.40) | CES2LMNAGAAMDM2 | |
| SCHEMBL11741375 | 0.80 | TAAR1 (0.38) | MAOB | |
| SCHEMBL11743542 | 0.80 | LPL (0.37) | LMNAGAA | |
| SCHEMBL11737101 | 0.78 | DPP4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52007959-A | — | — | None | — | — | JP | disclosed |
| JP-52031071-A | — | — | None | — | — | JP | disclosed |
| JP-52048663-A | — | — | None | — | — | JP | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
| CN-1143960-A | Therapeutic heterocyclic compounds | WELLCOME FOUND (GB) | 1997-02-26 | — | — | CN | disclosed |
| US-5545568-A | ARRAY OF COMPOUNDS ON SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1994006291-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF COMPOUNDS ON A SOLID SUPPORT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5288514-A | Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-22 | — | — | US | disclosed |
| US-4062862-A | MUSCLE RELAXANT | NIPPON CHEMIPHAR CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
| US-4062862-A | MUSCLE RELAXANT | NIPPON CHEMIPHAR CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
| US-4062862-A | MUSCLE RELAXANT | NIPPON CHEMIPHAR CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
| JP-S5248663-A | PREPARATION OF 5-BENZYL-2-OXAZOLIDONE DERIVATIVES | NIPPON CHEMIPHAR CO LTD | 1977-04-18 | — | — | JP | disclosed |
| JP-S5231071-A | 5-BENZYL-2-OXAZOLIDONE DERIVATIVES | NIPPON CHEMIPHAR CO LTD | 1977-03-09 | — | — | JP | disclosed |
| JP-S527959-A | PREPARATION OF 5-BENZYL-2-OXAZOLIDONE DERIVATIVES | NIPPON CHEMIPHAR CO LTD | 1977-01-21 | — | — | JP | disclosed |